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Disputation Katinka Becker

15.07.2021 | 14:00
Thema der Dissertation:
Logical Analysis of Biological Data
Thema der Disputation:
Characterizing Clear Cell Renal Cell Carcinoma using Logical Analysis of Data
Abstract: Efficient algorithms are essential for data analysis in life sciences.
Based on a study on the molecular stratification of the Clear Cell Renal Cell Carcinoma (ccRCC) [Brannon et al. (2010)] we discuss the capabilities of Logical Analysis of Data (LAD) for the investigation of biological data sets.
Pattern generation is a central problem in LAD. We give an insight in pattern types and algorithms. We further outline on the example of the ccRCC how LAD patterns are used for successful classification in practice and how they are employed by Brannon et al. to describe the pathway activations in two distinct tumor subtypes.

Zeit & Ort

15.07.2021 | 14:00