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Disputation Jörg Winkler

Sep 08, 2023 | 10:00 AM
Thema der Dissertation:
Algorithms for finding RNA sequence-structure motif
Thema der Disputation:
Why is predicting RNA structure so hard?
Lessons from machine learning-based protein structure prediction
Abstract: The problem of protein structure prediction is considered solved since AlphaFold 2 has entered the field applying a novel machine learning technique. However, the prediction of RNA structure remains a challenging task, despite the analogy that a molecular sequence bonds with itself and builds complex structural conformations that determine its functionality. The accurate determination of RNA structure is essential for understanding its functions, which include catalyzing biochemical reactions and regulating gene expression. In this talk, I discuss which opportunities and obstacles exist to transfer the success of protein structure prediction to the field of RNA.

Time & Location

Sep 08, 2023 | 10:00 AM

Seminarraum 049
(Fachbereich Mathematik und Informatik, Takustr.9, 14195 Berlin)