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Knut Reinert
Progress in medicine and life sciences becomes more and more dependent on complex workflows for data analysis. The immensely increasing amount of data that scientists are faced with demands a continuous improvement in these workflows as well as efficient algorithms and tools. CIBI ...
Jul 01, 2020 — Jun 30, 2024
Foundations for Large-Scale Scientific Data Analysis Workflows Essentially all scientific disciplines are generating an ever-increasing amount of data. To derive scientific discoveries, these data sets are analyzed by complex data analysis workflows (DAWs), which are series of discrete analysis ...
Determination of individual genomic variation from short- and long-read sequencing technologies Current sequencing technologies make if feasible to determine an individual's genome sequence and to identify possible disease causing variants. Most notably, structural variations can be identified ...
Live Analysis of Pathogen NGS Data using Dynamic Compressible Indices Next Generation Sequencing (NGS) has evolved as a main workhorse not only for molecular biology, but has also increasingly been used in clinical settings. For instance, unbiased, open-view pathogen diagnostics or personalized ...
Prof. Knut Reinert
Non-coding RNAs (ncRNAs), transcripts that do not code for proteins, started receiving a lot of attention in the last decade, thanks to several high-throughput genome-wide sequencing efforts which showed that, whereas less than 2% of the genome encodes proteins, at least 75% is actively ...
The analysis of sequencing data is demanding because of the enormous data volume and the need for fast turnaround time, accuracy, reproducibility, and data security. This requires a large variety of expertise: Algorithm design, strong implementation skills for analyzing big data on standard ...
OpenMS - A C++ library for MS based Proteomics analysis The OpenMS library is intended to provide a flexible framework for the differential analysis of HPLC/MS data. OpenMS offers algorithms for peak picking, protein ID, labeled and label-free quantitation. OpenMS has been ...
Prof. Knut Reinet
A C++ library for biological sequence analysis SeqAn is an open source C++ library of efficient algorithms and data structures for the analysis of sequences with the focus on biological data. Our library applies a unique generic design that guarantees high performance, ...
