In the seminar we discuss important and recent research results in the field of algorithmic genome comparison. The seminar can be accounted under "Studienbereich" C or D. In the new MSC Regulations it is W2 B. The goal of the seminar is twofold: 1. The participants should get an insight of the current research in the field 2. The participants will practice to read original research articles, work through them and present the gist of it in a coherent form to the other participants. The mark will be given according to the quality of the slides, the oral representation and the level of participation.